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Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits
It has been suggested that pharmacogenomic phenotypes are influenced by genetic variants with larger effect sizes than other phenotypes, such as complex disease risk. This is presumed to reflect the fact that relevant environmental factors (drug exposure) are appropriately measured and taken into ac...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704992/ https://www.ncbi.nlm.nih.gov/pubmed/26149738 http://dx.doi.org/10.1038/tpj.2015.47 |