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A Hybrid Approach for CpG Island Detection in the Human Genome

BACKGROUND: CpG islands have been demonstrated to influence local chromatin structures and simplify the regulation of gene activity. However, the accurate and rapid determination of CpG islands for whole DNA sequences remains experimentally and computationally challenging. METHODOLOGY/PRINCIPAL FIND...

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Detalles Bibliográficos
Autores principales: Yang, Cheng-Hong, Lin, Yu-Da, Chiang, Yi-Cheng, Chuang, Li-Yeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705099/
https://www.ncbi.nlm.nih.gov/pubmed/26727213
http://dx.doi.org/10.1371/journal.pone.0144748