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A Hybrid Approach for CpG Island Detection in the Human Genome
BACKGROUND: CpG islands have been demonstrated to influence local chromatin structures and simplify the regulation of gene activity. However, the accurate and rapid determination of CpG islands for whole DNA sequences remains experimentally and computationally challenging. METHODOLOGY/PRINCIPAL FIND...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705099/ https://www.ncbi.nlm.nih.gov/pubmed/26727213 http://dx.doi.org/10.1371/journal.pone.0144748 |