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Survivin contributes to DNA repair by homologous recombination in breast cancer cells

Survivin overexpression, frequently found in breast cancers and others, is associated with poor prognosis. Its dual regulation of cell division and apoptosis makes it an attractive therapeutic target but its exact functions that are required for tumor maintenance are still elusive. Survivin protects...

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Detalles Bibliográficos
Autores principales: Véquaud, Eloïse, Desplanques, Grégoire, Jézéquel, Pascal, Juin, Philippe, Barillé-Nion, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705120/
https://www.ncbi.nlm.nih.gov/pubmed/26679694
http://dx.doi.org/10.1007/s10549-015-3657-z