Reversible transformation and de-differentiation of human cells derived from induced pluripotent stem cell teratomas

We first aimed to generate transformed cell lines from a human induced pluripotent stem cell (hiPSC)-teratoma, and then examined the tumorigenic risks of the differentiated cells from hiPSC explant, because hiPSC-derivatives give rise to tumors in immune-deficient mice when transplanted. The colonie...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamada, Mizuna, Mitsui, Youji, Matsuo, Taira, Takahashi, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705144/
https://www.ncbi.nlm.nih.gov/pubmed/26069211
http://dx.doi.org/10.1007/s13577-015-0119-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705144/
https://www.ncbi.nlm.nih.gov/pubmed/26069211
http://dx.doi.org/10.1007/s13577-015-0119-1

Ejemplares similares