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Reversible transformation and de-differentiation of human cells derived from induced pluripotent stem cell teratomas

We first aimed to generate transformed cell lines from a human induced pluripotent stem cell (hiPSC)-teratoma, and then examined the tumorigenic risks of the differentiated cells from hiPSC explant, because hiPSC-derivatives give rise to tumors in immune-deficient mice when transplanted. The colonie...

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Detalles Bibliográficos
Autores principales:	Kamada, Mizuna, Mitsui, Youji, Matsuo, Taira, Takahashi, Tomoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Japan 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705144/ https://www.ncbi.nlm.nih.gov/pubmed/26069211 http://dx.doi.org/10.1007/s13577-015-0119-1

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