The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration

The maintenance and regulation of proteostasis is a critical function for post-mitotic neurons and its dysregulation is increasingly implicated in neurodegenerative diseases. Despite having different clinical manifestations, these disorders share similar pathology; an accumulation of misfolded prote...

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Detalles Bibliográficos
Autores principales: Perri, Emma R., Thomas, Colleen J., Parakh, Sonam, Spencer, Damian M., Atkin, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705227/
https://www.ncbi.nlm.nih.gov/pubmed/26779479
http://dx.doi.org/10.3389/fcell.2015.00080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705227/
https://www.ncbi.nlm.nih.gov/pubmed/26779479
http://dx.doi.org/10.3389/fcell.2015.00080

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