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The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration

The maintenance and regulation of proteostasis is a critical function for post-mitotic neurons and its dysregulation is increasingly implicated in neurodegenerative diseases. Despite having different clinical manifestations, these disorders share similar pathology; an accumulation of misfolded prote...

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Detalles Bibliográficos
Autores principales:	Perri, Emma R., Thomas, Colleen J., Parakh, Sonam, Spencer, Damian M., Atkin, Julie D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705227/ https://www.ncbi.nlm.nih.gov/pubmed/26779479 http://dx.doi.org/10.3389/fcell.2015.00080

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