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DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites

The DISC1 protein is implicated in major mental illnesses including schizophrenia, depression, bipolar disorder, and autism. Aberrant mitochondrial dynamics are also associated with major mental illness. DISC1 plays a role in mitochondrial transport in neuronal axons, but its effects in dendrites ha...

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Detalles Bibliográficos
Autores principales: Norkett, Rosalind, Modi, Souvik, Birsa, Nicol, Atkin, Talia A., Ivankovic, Davor, Pathania, Manav, Trossbach, Svenja V., Korth, Carsten, Hirst, Warren D., Kittler, Josef T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705382/
https://www.ncbi.nlm.nih.gov/pubmed/26553875
http://dx.doi.org/10.1074/jbc.M115.699447