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High proportions of regulatory T cells in PBSC grafts predict improved survival after allogeneic haematopoietic SCT

Regulatory T cells (Tregs) modulate immune responses and improve survival in murine transplant models. However, whether the Treg content of allogeneic cell grafts influences the outcome in human haematopoietic stem cell (HSC) transplantation is not well established. In a prospective study of 94 adul...

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Detalles Bibliográficos
Autores principales: Danby, R D, Zhang, W, Medd, P, Littlewood, T J, Peniket, A, Rocha, V, Roberts, D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705424/
https://www.ncbi.nlm.nih.gov/pubmed/26389831
http://dx.doi.org/10.1038/bmt.2015.215