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High proportions of regulatory T cells in PBSC grafts predict improved survival after allogeneic haematopoietic SCT
Regulatory T cells (Tregs) modulate immune responses and improve survival in murine transplant models. However, whether the Treg content of allogeneic cell grafts influences the outcome in human haematopoietic stem cell (HSC) transplantation is not well established. In a prospective study of 94 adul...
Autores principales: | Danby, R D, Zhang, W, Medd, P, Littlewood, T J, Peniket, A, Rocha, V, Roberts, D J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705424/ https://www.ncbi.nlm.nih.gov/pubmed/26389831 http://dx.doi.org/10.1038/bmt.2015.215 |
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