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Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development

The JAK-STAT pathway has a substantial role in lymphoid precursor cell proliferation, survival and differentiation. Nonetheless, the contribution of JAK2 to T-cell lymphoblastic lymphoma (T-LBL) development remains poorly understood. We have identified one activating TEL-JAK2 translocation and four...

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Detalles Bibliográficos
Autores principales: Roncero, A M, López-Nieva, P, Cobos-Fernández, M A, Villa-Morales, M, González-Sánchez, L, López-Lorenzo, J L, Llamas, P, Ayuso, C, Rodríguez-Pinilla, S M, Arriba, M C, Piris, M A, Fernández-Navarro, P, Fernández, A F, Fraga, M F, Santos, J, Fernández-Piqueras, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705429/
https://www.ncbi.nlm.nih.gov/pubmed/26216197
http://dx.doi.org/10.1038/leu.2015.202