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Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease

Infection of subcutaneous tissue with Mycobacterium ulcerans can lead to chronic skin ulceration known as Buruli ulcer. The pathogenesis of this neglected tropical disease is dependent on a lipid‐like toxin, mycolactone, which diffuses through tissue away from the infecting organisms. Since its iden...

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Detalles Bibliográficos
Autores principales: Sarfo, Fred Stephen, Phillips, Richard, Wansbrough‐Jones, Mark, Simmonds, Rachel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705457/
https://www.ncbi.nlm.nih.gov/pubmed/26572803
http://dx.doi.org/10.1111/cmi.12547