Thermodynamics and kinetics of amphotericin B self-association in aqueous solution characterized in molecular detail

Amphotericin B (AmB) is a potent but toxic drug commonly used to treat systemic mycoses. Its efficiency as a therapeutic agent depends on its ability to discriminate between mammalian and fungal cell membranes. The association of AmB monomers in an aqueous environment plays an important role in drug...

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Detalles Bibliográficos
Autores principales: Zielińska, Joanna, Wieczór, Miłosz, Bączek, Tomasz, Gruszecki, Marcin, Czub, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705489/
https://www.ncbi.nlm.nih.gov/pubmed/26742886
http://dx.doi.org/10.1038/srep19109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705489/
https://www.ncbi.nlm.nih.gov/pubmed/26742886
http://dx.doi.org/10.1038/srep19109

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