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Sertoli cells have a functional NALP3 inflammasome that can modulate autophagy and cytokine production

Sertoli cells, can function as non-professional tolerogenic antigen-presenting cells, and sustain the blood-testis barrier formed by their tight junctions. The NOD-like receptor family members and the NALP3 inflammasome play a key role in pro-inflammatory innate immunity signalling pathways. Limited...

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Detalles Bibliográficos
Autores principales: Hayrabedyan, Soren, Todorova, Krassimira, Jabeen, Asma, Metodieva, Gergana, Toshkov, Stavri, Metodiev, Metodi V., Mincheff, Milcho, Fernández, Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705529/
https://www.ncbi.nlm.nih.gov/pubmed/26744177
http://dx.doi.org/10.1038/srep18896