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17beta-estradiol counteracts neuropathic pain: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice

Sex differences play a role in pain sensitivity, efficacy of analgesic drugs and prevalence of neuropathic pain, even if the underlying mechanisms are far from being understood. We demonstrate that male and female mice react differently to structural and functional changes induced by sciatic nerve l...

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Detalles Bibliográficos
Autores principales: Vacca, Valentina, Marinelli, Sara, Pieroni, Luisa, Urbani, Andrea, Luvisetto, Siro, Pavone, Flaminia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705539/
https://www.ncbi.nlm.nih.gov/pubmed/26742647
http://dx.doi.org/10.1038/srep18980