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17beta-estradiol counteracts neuropathic pain: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice
Sex differences play a role in pain sensitivity, efficacy of analgesic drugs and prevalence of neuropathic pain, even if the underlying mechanisms are far from being understood. We demonstrate that male and female mice react differently to structural and functional changes induced by sciatic nerve l...
Autores principales: | Vacca, Valentina, Marinelli, Sara, Pieroni, Luisa, Urbani, Andrea, Luvisetto, Siro, Pavone, Flaminia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705539/ https://www.ncbi.nlm.nih.gov/pubmed/26742647 http://dx.doi.org/10.1038/srep18980 |
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