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Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles

BACKGROUND: Poly(alkyl cyanoacrylate) (PACA) nanoparticles have shown promise as drug carriers both to solid tumors and across the blood–brain barrier. Efficient drug delivery requires both high cellular uptake of the nanoparticles and release of the drug from the nanoparticles. Release of hydrophob...

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Detalles Bibliográficos
Autores principales: Sulheim, Einar, Baghirov, Habib, von Haartman, Eva, Bøe, Andreas, Åslund, Andreas K. O., Mørch, Yrr, Davies, Catharina de Lange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705582/
https://www.ncbi.nlm.nih.gov/pubmed/26743777
http://dx.doi.org/10.1186/s12951-015-0156-7