Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis

Metabolic changes can influence inflammatory responses to bacteria. To examine whether localized manipulation of the mevalonate pathway impacts innate immunity, we exploited a unique mucosal disease model, endometritis, where inflammation is a consequence of innate immunity. IL responses to pathogen...

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Detalles Bibliográficos
Autores principales: Healey, Gareth D., Collier, Christine, Griffin, Sholeem, Schuberth, Hans-Joachim, Sandra, Olivier, Smith, David G., Mahan, Suman, Dieuzy-Labaye, Isabelle, Sheldon, I. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Innate Immunity and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705593/
https://www.ncbi.nlm.nih.gov/pubmed/26673142
http://dx.doi.org/10.4049/jimmunol.1501080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705593/
https://www.ncbi.nlm.nih.gov/pubmed/26673142
http://dx.doi.org/10.4049/jimmunol.1501080

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