Cargando…

Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis

Metabolic changes can influence inflammatory responses to bacteria. To examine whether localized manipulation of the mevalonate pathway impacts innate immunity, we exploited a unique mucosal disease model, endometritis, where inflammation is a consequence of innate immunity. IL responses to pathogen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Healey, Gareth D., Collier, Christine, Griffin, Sholeem, Schuberth, Hans-Joachim, Sandra, Olivier, Smith, David G., Mahan, Suman, Dieuzy-Labaye, Isabelle, Sheldon, I. Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2016
Materias:	Innate Immunity and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705593/ https://www.ncbi.nlm.nih.gov/pubmed/26673142 http://dx.doi.org/10.4049/jimmunol.1501080

Ejemplares similares

Composition, Development, and Function of Uterine Innate Lymphoid Cells
por: Doisne, Jean-Marc, et al.
Publicado: (2015)

Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements
por: Millrine, David, et al.
Publicado: (2023)

The Polyamine Putrescine Is a Positive Regulator of Group 3 Innate Lymphocyte Activation
por: Sah, Prakash, et al.
Publicado: (2023)

TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN
por: Temizoz, Burcu, et al.
Publicado: (2015)

Assessing the Impact of Persistent HIV Infection on Innate Lymphoid Cells Using In Vitro Models
por: Boulay, Aude, et al.
Publicado: (2023)

Decidual Neutrophil Infiltration Is Not Required for Preterm Birth in a Mouse Model of Infection-Induced Preterm Labor
por: Rinaldi, Sara F., et al.
Publicado: (2014)

TLR-Mediated Inflammatory Responses to Streptococcus pneumoniae Are Highly Dependent on Surface Expression of Bacterial Lipoproteins
por: Tomlinson, Gillian, et al.
Publicado: (2014)

Regulation of Neutrophilic Inflammation by Proteinase-Activated Receptor 1 during Bacterial Pulmonary Infection
por: José, Ricardo J., et al.
Publicado: (2015)

The Processed Amino-Terminal Fragment of Human TLR7 Acts as a Chaperone To Direct Human TLR7 into Endosomes
por: Hipp, Madeleine M., et al.
Publicado: (2015)

IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism
por: Sanin, David E., et al.
Publicado: (2015)

Definition of a Novel Pathway Centered on Lysophosphatidic Acid To Recruit Monocytes during the Resolution Phase of Tissue Inflammation
por: McArthur, Simon, et al.
Publicado: (2015)

Protective Role for Caspase-11 during Acute Experimental Murine Colitis
por: Oficjalska, Katarzyna, et al.
Publicado: (2015)

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin
por: Ross, Ewan A., et al.
Publicado: (2015)

Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide
por: Smallie, Tim, et al.
Publicado: (2015)

Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9
por: Georgiannakis, Apostolos, et al.
Publicado: (2015)

Enforced Expression of Hoxa3 Inhibits Classical and Promotes Alternative Activation of Macrophages In Vitro and In Vivo
por: Al Sadoun, Hadeel, et al.
Publicado: (2016)

PTPN22 Is a Critical Regulator of Fcγ Receptor–Mediated Neutrophil Activation
por: Vermeren, Sonja, et al.
Publicado: (2016)

Cell-Autonomous Sex Differences in Gene Expression in Chicken Bone Marrow–Derived Macrophages
por: Garcia-Morales, Carla, et al.
Publicado: (2015)

Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages
por: Howes, Ashleigh, et al.
Publicado: (2016)

IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production
por: Wagstaffe, Helen R., et al.
Publicado: (2018)

Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1
por: Walwyn-Brown, Katherine, et al.
Publicado: (2018)

Viral Resistance and IFN Signaling in STAT2 Knockout Fish Cells
por: Dehler, Carola E., et al.
Publicado: (2019)

Monocyte Subsets Coregulate Inflammatory Responses by Integrated Signaling through TNF and IL-6 at the Endothelial Cell Interface
por: Chimen, Myriam, et al.
Publicado: (2017)

Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions
por: Dragoni, Silvia, et al.
Publicado: (2017)

Hydrogen Peroxide Triggers a Dual Signaling Axis To Selectively Suppress Activated Human T Lymphocyte Migration
por: Ball, Jennifer A., et al.
Publicado: (2017)

Targeting Neutrophilic Inflammation Using Polymersome-Mediated Cellular Delivery
por: Robertson, James D., et al.
Publicado: (2017)

Activated Microglia Desialylate and Phagocytose Cells via Neuraminidase, Galectin-3, and Mer Tyrosine Kinase
por: Nomura, Koji, et al.
Publicado: (2017)

ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
por: Reyat, Jasmeet S., et al.
Publicado: (2017)

Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection
por: Goodier, Martin R., et al.
Publicado: (2016)

A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites
por: McCormick, Barry, et al.
Publicado: (2019)

The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix
por: Taylor, Scott, et al.
Publicado: (2020)

IL-18 Binding Protein–Producing Cells Attenuate Anemia in Murine Macrophage Activation Syndrome
por: Harel, Mathilde, et al.
Publicado: (2023)

B Lymphocyte–Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury
por: Inaba, Akimichi, et al.
Publicado: (2020)

Direct Antiviral Activity of IFN-Stimulated Genes Is Responsible for Resistance to Paramyxoviruses in ISG15-Deficient Cells
por: Holthaus, David, et al.
Publicado: (2020)

Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor Signaling
por: Pionnier, Nicolas, et al.
Publicado: (2020)

Defining the Glycosaminoglycan Interactions of Complement Factor H–Related Protein 5
por: Gyapon-Quast, Frederick, et al.
Publicado: (2021)

Dendritic Cell–Specific Role for Pellino2 as a Mediator of TLR9 Signaling Pathway
por: Oleszycka, Ewa, et al.
Publicado: (2021)

Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood
por: Storm, Benjamin S., et al.
Publicado: (2021)

TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages
por: Blair, Louise, et al.
Publicado: (2022)

TNF-α Regulates Human Plasmacytoid Dendritic Cells by Suppressing IFN-α Production and Enhancing T Cell Activation
por: Psarras, Antonios, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qkbsfo9u885epqljk9vnj3k8vp