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In vitro and in vivo evaluation of cord blood hematopoietic stem and progenitor cells amplified with glycosaminoglycan mimetic

BACKGROUND: Expansion protocols aim at both increasing the number of umbilical cord blood (UCB) hematopoietic stem cells and progenitor cells (HSPCs) and reducing the period of neutropenia in UCB HSPC graft. Because glycosaminoglycans (GAGs) are known to be important components of the hematopoietic...

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Detalles Bibliográficos
Autores principales: Faivre, Lionel, Parietti, Véronique, Siñeriz, Fernando, Chantepie, Sandrine, Gilbert-Sirieix, Marie, Albanese, Patricia, Larghero, Jérôme, Vanneaux, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705640/
https://www.ncbi.nlm.nih.gov/pubmed/26742480
http://dx.doi.org/10.1186/s13287-015-0267-y