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Mcm10 coordinates the timely assembly and activation of the replication fork helicase

Mcm10 is an essential replication factor that is required for DNA replication in eukaryotes. Two key steps in the initiation of DNA replication are the assembly and activation of Cdc45–Mcm2–7-GINS (CMG) replicative helicase. However, it is not known what coordinates helicase assembly with helicase a...

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Detalles Bibliográficos
Autores principales: Perez-Arnaiz, Patricia, Bruck, Irina, Kaplan, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705653/
https://www.ncbi.nlm.nih.gov/pubmed/26582917
http://dx.doi.org/10.1093/nar/gkv1260