A general strategy to inhibiting viral −1 frameshifting based on upstream attenuation duplex formation

Viral −1 programmed ribosomal frameshifting (PRF) as a potential antiviral target has attracted interest because many human viral pathogens, including human immunodeficiency virus (HIV) and coronaviruses, rely on −1 PRF for optimal propagation. Efficient eukaryotic −1 PRF requires an optimally place...

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Detalles Bibliográficos
Autores principales: Hu, Hao-Teng, Cho, Che-Pei, Lin, Ya-Hui, Chang, Kung-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705660/
https://www.ncbi.nlm.nih.gov/pubmed/26612863
http://dx.doi.org/10.1093/nar/gkv1307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705660/
https://www.ncbi.nlm.nih.gov/pubmed/26612863
http://dx.doi.org/10.1093/nar/gkv1307

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