Folding dynamics and conformational heterogeneity of human telomeric G-quadruplex structures in Na(+) solutions by single molecule FRET microscopy

G-quadruplex structures can occur throughout the genome, including at telomeres. They are involved in cellular regulation and are potential drug targets. Human telomeric G-quadruplex structures can fold into a number of different conformations and show large conformational diversity. To elucidate th...

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Detalles Bibliográficos
Autores principales: Noer, Sofie L., Preus, Søren, Gudnason, Daniel, Aznauryan, Mikayel, Mergny, Jean-Louis, Birkedal, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705662/
https://www.ncbi.nlm.nih.gov/pubmed/26615192
http://dx.doi.org/10.1093/nar/gkv1320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705662/
https://www.ncbi.nlm.nih.gov/pubmed/26615192
http://dx.doi.org/10.1093/nar/gkv1320

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