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RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1

Ribonucleases are critically important in many cellular and developmental processes and defects in their expression are associated with human disease. Pacman/XRN1 is a highly conserved cytoplasmic exoribonuclease which degrades RNAs in a 5′-3′ direction. In Drosophila, null mutations in pacman resul...

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Detalles Bibliográficos
Autores principales: Jones, Christopher I., Pashler, Amy L., Towler, Benjamin P., Robinson, Sophie R., Newbury, Sarah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705666/
https://www.ncbi.nlm.nih.gov/pubmed/26656493
http://dx.doi.org/10.1093/nar/gkv1336