Cargando…

L1 retrotransposition requires rapid ORF1p oligomerization, a novel coiled coil-dependent property conserved despite extensive remodeling

Detailed mechanistic understanding of L1 retrotransposition is sparse, particularly with respect to ORF1p, a coiled coil-mediated homotrimeric nucleic acid chaperone that can form tightly packed oligomers on nucleic acids. Although the coiled coil motif is highly conserved, it is uniquely susceptibl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naufer, M. Nabuan, Callahan, Kathryn E., Cook, Pamela R., Perez-Gonzalez, Cesar E., Williams, Mark C., Furano, Anthony V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705668/ https://www.ncbi.nlm.nih.gov/pubmed/26673717 http://dx.doi.org/10.1093/nar/gkv1342

Ejemplares similares

The L1-ORF1p coiled coil enables formation of a tightly compacted nucleic acid-bound complex that is associated with retrotransposition
por: Cashen, Ben A, et al.
Publicado: (2022)

Protein-nucleic acid interactions of LINE-1 ORF1p
por: Naufer, M. Nabuan, et al.
Publicado: (2018)

Cryptic genetic variation enhances primate L1 retrotransposon survival by enlarging the functional coiled coil sequence space of ORF1p
por: Furano, Anthony V., et al.
Publicado: (2020)

Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p
por: Khazina, Elena, et al.
Publicado: (2018)

Molecular Mechanism of STIL Coiled-Coil Domain Oligomerization
por: Shamir, Mai, et al.
Publicado: (2023)

Co-expression of distinct L1 retrotransposon coiled coils can lead to their entanglement
por: Mizgier, Nikola A., et al.
Publicado: (2023)

The Coiled Coils of Cohesin Are Conserved in Animals, but Not In Yeast
por: White, Glenn E., et al.
Publicado: (2009)

Multicoil2: Predicting Coiled Coils and Their Oligomerization States from Sequence in the Twilight Zone
por: Trigg, Jason, et al.
Publicado: (2011)

Oligomeric Coiled-Coil Adhesin YadA Is a Double-Edged Sword
por: Casutt-Meyer, Salome, et al.
Publicado: (2010)

Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb
por: Blazek, Dalibor, et al.
Publicado: (2005)

Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant
por: Bjelić, Saša, et al.
Publicado: (2013)

Complex Networks Govern Coiled-Coil Oligomerization – Predicting and Profiling by Means of a Machine Learning Approach
por: Mahrenholz, Carsten C., et al.
Publicado: (2011)

Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR)
por: Christian, Claiborne M., et al.
Publicado: (2016)

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins
por: Caillat, Christophe, et al.
Publicado: (2015)

A “Coiled-Coil” Motif Is Important for Oligomerization and DNA Binding Properties of Human Cytomegalovirus Protein UL77
por: Meissner, Christina Sylvia, et al.
Publicado: (2011)

Coiled coils 9-to-5: rational de novo design of α-helical barrels with tunable oligomeric states
por: Dawson, William M., et al.
Publicado: (2021)

Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans
por: Sokolowski, Mark, et al.
Publicado: (2017)

Molecular basis of the STIL coiled coil oligomerization explains its requirement for de-novo formation of centrosomes in mammalian cells
por: David, Ahuvit, et al.
Publicado: (2016)

Directed assembly of defined oligomeric photosynthetic reaction centres through adaptation with programmable extra-membrane coiled-coil interfaces
por: Swainsbury, David J.K., et al.
Publicado: (2016)

Oligomerization-primed coiled-coil domain interaction with Ubc13 confers processivity to TRAF6 ubiquitin ligase activity
por: Hu, Lin, et al.
Publicado: (2017)

Structural implications of conserved aspartate residues located in tropomyosin’s coiled-coil core
por: Moore, Jeffrey R., et al.
Publicado: (2011)

Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition
por: Goodier, John L., et al.
Publicado: (2013)

ARCIMBOLDO on coiled coils
por: Caballero, Iracema, et al.
Publicado: (2018)

Classification of the human THAP protein family identifies an evolutionarily conserved coiled coil region
por: Sanghavi, Hiral M., et al.
Publicado: (2019)

The RNA Polymerase Dictates ORF1 Requirement and Timing of LINE and SINE Retrotransposition
por: Kroutter, Emily N., et al.
Publicado: (2009)

Polymerization and nucleic acid-binding properties of human L1 ORF1 protein
por: Callahan, Kathryn E., et al.
Publicado: (2012)

EML1–ABL1 Is Activated by Coiled-Coil-Mediated Oligomerization and Induces T-Cell Acute Lymphoblastic Leukemia or Myeloproliferative Disease in a Mouse Bone Marrow Transplant Model
por: Vanden Bempt, Marlies, et al.
Publicado: (2018)

The ORF1 Protein Encoded by LINE-1: Structure and Function During L1 Retrotransposition
por: Martin, Sandra L.
Publicado: (2006)

Extensive somatic L1 retrotransposition in colorectal tumors
por: Solyom, Szilvia, et al.
Publicado: (2012)

Development of a Platform for Noncovalent Coupling of Full Antigens to Tobacco Etch Virus-Like Particles by Means of Coiled-Coil Oligomerization Motifs
por: Zapata-Cuellar, Lorena, et al.
Publicado: (2021)

Magnetic measurements with the helmholtz coil and the potential coil
por: Steingroever, E, et al.
Publicado: (1997)

α/β coiled coils
por: Hartmann, Marcus D, et al.
Publicado: (2016)

Evolutionary Patterns in Coiled-Coils
por: Surkont, Jaroslaw, et al.
Publicado: (2015)

Coiled‐coils: The long and short of it
por: Truebestein, Linda, et al.
Publicado: (2016)

APOBEC3G Oligomerization Is Associated with the Inhibition of Both Alu and LINE-1 Retrotransposition
por: Koyama, Takayoshi, et al.
Publicado: (2013)

Sequence Conservation in Plasmodium falciparum α-Helical Coiled Coil Domains Proposed for Vaccine Development
por: Kulangara, Caroline, et al.
Publicado: (2009)

Correction to: Classification of the human THAP protein family identifies an evolutionarily conserved coiled coil region
por: Sanghavi, Hiral M., et al.
Publicado: (2019)

PcrG protects the two long helical oligomerization domains of PcrV, by an interaction mediated by the intramolecular coiled-coil region of PcrG
por: Basu, Abhishek, et al.
Publicado: (2014)

Solving coiled-coil protein structures
por: Dauter, Zbigniew
Publicado: (2015)

The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis
por: Hodeify, Rawad, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ralam6648n8ldtn460jnjuqlkv