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Identification of large-scale genomic variation in cancer genomes using in silico reference models
Identifying large-scale structural variation in cancer genomes continues to be a challenge to researchers. Current methods rely on genome alignments based on a reference that can be a poor fit to highly variant and complex tumor genomes. To address this challenge we developed a method that uses avai...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705683/ https://www.ncbi.nlm.nih.gov/pubmed/26264669 http://dx.doi.org/10.1093/nar/gkv828 |