Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon

Mycobacterium tuberculosis (Mtb) Cmr (Rv1675c) is a CRP/FNR family transcription factor known to be responsive to cAMP levels and during macrophage infections. However, Cmr's DNA binding properties, cellular targets and overall role in tuberculosis (TB) complex bacteria have not been characteri...

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Detalles Bibliográficos
Autores principales: Ranganathan, Sridevi, Bai, Guangchun, Lyubetskaya, Anna, Knapp, Gwendowlyn S., Peterson, Matthew W., Gazdik, Michaela, C. Gomes, Antonio L., Galagan, James E., McDonough, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705688/
https://www.ncbi.nlm.nih.gov/pubmed/26358810
http://dx.doi.org/10.1093/nar/gkv889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705688/
https://www.ncbi.nlm.nih.gov/pubmed/26358810
http://dx.doi.org/10.1093/nar/gkv889

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