Characterization of a novel DNA glycosylase from S. sahachiroi involved in the reduction and repair of azinomycin B induced DNA damage

Azinomycin B is a hybrid polyketide/nonribosomal peptide natural product and possesses antitumor activity by interacting covalently with duplex DNA and inducing interstrand crosslinks. In the biosynthetic study of azinomycin B, a gene (orf1) adjacent to the azinomycin B gene cluster was found to be...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Liu, Kai, Xiao, Le, Yang, LiYuan, Li, Hong, Zhang, FeiXue, Lei, Lei, Li, ShengQing, Feng, Xu, Li, AiYing, He, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705692/
https://www.ncbi.nlm.nih.gov/pubmed/26400161
http://dx.doi.org/10.1093/nar/gkv949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705692/
https://www.ncbi.nlm.nih.gov/pubmed/26400161
http://dx.doi.org/10.1093/nar/gkv949

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