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Acentric chromosome ends are prone to fusion with functional chromosome ends through a homology-directed rearrangement

The centromeres of many eukaryotic chromosomes are established epigenetically on potentially variable tandem repeats; hence, these chromosomes are at risk of being acentric. We reported previously that artificially created acentric chromosomes in the fission yeast Schizosaccharomyces pombe can be re...

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Detalles Bibliográficos
Autores principales: Ohno, Yuko, Ogiyama, Yuki, Kubota, Yoshino, Kubo, Takuya, Ishii, Kojiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705696/
https://www.ncbi.nlm.nih.gov/pubmed/26433224
http://dx.doi.org/10.1093/nar/gkv997