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Ultra-deep sequencing of VHSV isolates contributes to understanding the role of viral quasispecies

The high mutation rate of RNA viruses enables the generation of a genetically diverse viral population, termed a quasispecies, within a single infected host. This high in-host genetic diversity enables an RNA virus to adapt to a diverse array of selective pressures such as host immune response and s...

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Detalles Bibliográficos
Autores principales: Schönherz, Anna A., Lorenzen, Niels, Guldbrandtsen, Bernt, Buitenhuis, Bart, Einer-Jensen, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705744/
https://www.ncbi.nlm.nih.gov/pubmed/26743117
http://dx.doi.org/10.1186/s13567-015-0298-5