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Ultra-deep sequencing of VHSV isolates contributes to understanding the role of viral quasispecies
The high mutation rate of RNA viruses enables the generation of a genetically diverse viral population, termed a quasispecies, within a single infected host. This high in-host genetic diversity enables an RNA virus to adapt to a diverse array of selective pressures such as host immune response and s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705744/ https://www.ncbi.nlm.nih.gov/pubmed/26743117 http://dx.doi.org/10.1186/s13567-015-0298-5 |