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An AU-rich instability element in the 3′UTR mediates an increase in mRNA stability in response to expression of a dhh1 ATPase mutant
The DEAD box RNA helicase DHH1 acts as a general repressor of translation and activator of decapping but can also act specifically on individual mRNAs. In trypanosomes, DHH1 overexpression or expression of a dhh1 ATPase mutant, dhh1 DEAD:DQAD, resulted in increased or decreased stability of a small...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705827/ https://www.ncbi.nlm.nih.gov/pubmed/26779405 http://dx.doi.org/10.4161/trla.28587 |