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Interactions between Myc and MondoA transcription factors in metabolism and tumourigenesis

Metabolic reprogramming towards aerobic glycolysis is a common feature of transformed cells and can be driven by a network of transcription factors. It is well established that c-Myc and hypoxia-inducible factor-1α (HIF-1α) contribute to metabolic reprogramming by driving the expression of glycolyti...

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Detalles Bibliográficos
Autores principales: Wilde, Blake R, Ayer, Donald E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705882/
https://www.ncbi.nlm.nih.gov/pubmed/26469830
http://dx.doi.org/10.1038/bjc.2015.360