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Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Proximal and Distal Colon

BACKGROUND & AIMS: Most knowledge about gastrointestinal (GI)-tract dendritic cells (DC) relies on murine studies where CD103(+) DC specialize in generating immune tolerance with the functionality of CD11b(+/−) subsets being unclear. Information about human GI-DC is scarce, especially regarding...

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Detalles Bibliográficos
Autores principales: Bernardo, David, Durant, Lydia, Mann, Elizabeth R., Bassity, Elizabeth, Montalvillo, Enrique, Man, Ripple, Vora, Rakesh, Reddi, Durga, Bayiroglu, Fahri, Fernández-Salazar, Luis, English, Nick R., Peake, Simon T.C., Landy, Jon, Lee, Gui H., Malietzis, George, Siaw, Yi Harn, Murugananthan, Aravinth U., Hendy, Phil, Sánchez-Recio, Eva, Phillips, Robin K.S., Garrote, Jose A., Scott, Paul, Parkhill, Julian, Paulsen, Malte, Hart, Ailsa L., Al-Hassi, Hafid O., Arranz, Eduardo, Walker, Alan W., Carding, Simon R., Knight, Stella C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705905/
https://www.ncbi.nlm.nih.gov/pubmed/26866054
http://dx.doi.org/10.1016/j.jcmgh.2015.08.006