Structural Insights into the MMACHC-MMADHC Protein Complex Involved in Vitamin B(12) Trafficking

Conversion of vitamin B(12) (cobalamin, Cbl) into the cofactor forms methyl-Cbl (MeCbl) and adenosyl-Cbl (AdoCbl) is required for the function of two crucial enzymes, mitochondrial methylmalonyl-CoA mutase and cytosolic methionine synthase, respectively. The intracellular proteins MMACHC and MMADHC...

Descripción completa

Detalles Bibliográficos
Autores principales: Froese, D. Sean, Kopec, Jolanta, Fitzpatrick, Fiona, Schuller, Marion, McCorvie, Thomas J., Chalk, Rod, Plessl, Tanja, Fettelschoss, Victoria, Fowler, Brian, Baumgartner, Matthias R., Yue, Wyatt W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705923/
https://www.ncbi.nlm.nih.gov/pubmed/26483544
http://dx.doi.org/10.1074/jbc.M115.683268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705923/
https://www.ncbi.nlm.nih.gov/pubmed/26483544
http://dx.doi.org/10.1074/jbc.M115.683268

Ejemplares similares