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Structural Insights into the MMACHC-MMADHC Protein Complex Involved in Vitamin B(12) Trafficking

Conversion of vitamin B(12) (cobalamin, Cbl) into the cofactor forms methyl-Cbl (MeCbl) and adenosyl-Cbl (AdoCbl) is required for the function of two crucial enzymes, mitochondrial methylmalonyl-CoA mutase and cytosolic methionine synthase, respectively. The intracellular proteins MMACHC and MMADHC...

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Detalles Bibliográficos
Autores principales:	Froese, D. Sean, Kopec, Jolanta, Fitzpatrick, Fiona, Schuller, Marion, McCorvie, Thomas J., Chalk, Rod, Plessl, Tanja, Fettelschoss, Victoria, Fowler, Brian, Baumgartner, Matthias R., Yue, Wyatt W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705923/ https://www.ncbi.nlm.nih.gov/pubmed/26483544 http://dx.doi.org/10.1074/jbc.M115.683268

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