Cargando…

Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP(2))

Sperm-specific phospholipase C-ζ (PLCζ) is widely considered to be the physiological stimulus that triggers intracellular Ca(2+) oscillations and egg activation during mammalian fertilization. Although PLCζ is structurally similar to PLCδ1, it lacks a pleckstrin homology domain, and it remains uncle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nomikos, Michail, Sanders, Jessica R., Parthimos, Dimitris, Buntwal, Luke, Calver, Brian L., Stamatiadis, Panagiotis, Smith, Adrian, Clue, Matthew, Sideratou, Zili, Swann, Karl, Lai, F. Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Lipids
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705952/ https://www.ncbi.nlm.nih.gov/pubmed/26429913 http://dx.doi.org/10.1074/jbc.M115.658443

Ejemplares similares

Phospholipase Cζ binding to PtdIns(4,5)P(2) requires the XY-linker region
por: Nomikos, Michail, et al.
Publicado: (2011)

Male infertility-linked point mutation disrupts the Ca(2+) oscillation-inducing and PIP(2) hydrolysis activity of sperm PLCζ
por: Nomikos, Michail, et al.
Publicado: (2011)

The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain
por: Heier, Christoph, et al.
Publicado: (2017)

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activity
por: Xie, Jia, et al.
Publicado: (2011)

Male infertility-linked point mutation disrupts the Ca(2+) oscillation-inducing and PIP(2) hydrolysis activity of sperm PLCζ
por: Nomikos, M., et al.
Publicado: (2011)

Patatin-like phospholipase domain–containing protein 3 promotes transfers of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets
por: Mitsche, Matthew A., et al.
Publicado: (2018)

ERRATUM: Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activity
por: Xie, Jia, et al.
Publicado: (2012)

A Reducing Milieu Renders Cofilin Insensitive to Phosphatidylinositol 4,5-Bisphosphate (PIP(2)) Inhibition
por: Schulte, Bianca, et al.
Publicado: (2013)

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) facilitates norepinephrine transporter dimerization and modulates substrate efflux
por: Luethi, Dino, et al.
Publicado: (2022)

Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase Cζ
por: Sanusi, Randa, et al.
Publicado: (2015)

Identification of postsynaptic phosphatidylinositol-4,5-bisphosphate (PIP(2)) roles for synaptic plasticity using chemically induced dimerization
por: Kim, Su-Jeong, et al.
Publicado: (2017)

Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D
por: Moreau, Kevin, et al.
Publicado: (2012)

A dPIP5K Dependent Pool of Phosphatidylinositol 4,5 Bisphosphate (PIP(2)) Is Required for G-Protein Coupled Signal Transduction in Drosophila Photoreceptors
por: Chakrabarti, Purbani, et al.
Publicado: (2015)

Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility
por: Nomikos, Michail, et al.
Publicado: (2013)

Phosphatidylinositol 4,5-bisphosphate in the Control of Membrane Trafficking
por: Li, Suhua, et al.
Publicado: (2020)

Structure and Lateral Organization of Phosphatidylinositol 4,5-bisphosphate
por: Borges-Araújo, Luís, et al.
Publicado: (2020)

Phosphatidylinositol-4-Phosphate 5-Kinases and Phosphatidylinositol 4,5-Bisphosphate Synthesis in the Brain
por: Volpicelli-Daley, Laura A., et al.
Publicado: (2010)

Amphetamine actions rely on the availability of phosphatidylinositol-4,5-bisphosphate
por: Buchmayer, Florian, et al.
Publicado: (2011)

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis
por: Walter, Alexander M, et al.
Publicado: (2017)

Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane
por: Katan, Matilda, et al.
Publicado: (2020)

Mutagenesis of the Phosphatidylinositol 4,5-Bisphosphate (Pip(2)) Binding Site in the Nh(2)-Terminal Domain of Ezrin Correlates with Its Altered Cellular Distribution
por: Barret, Cécile, et al.
Publicado: (2000)

Long-term depression in neurons involves temporal and ultra-structural dynamics of phosphatidylinositol-4,5-bisphosphate relying on PIP5K, PTEN and PLC
por: Hofbrucker-MacKenzie, Sarah A., et al.
Publicado: (2023)

Phospholipase C-related catalytically inactive protein regulates cytokinesis by protecting phosphatidylinositol 4,5-bisphosphate from metabolism in the cleavage furrow
por: Asano, Satoshi, et al.
Publicado: (2019)

Identification of Plant-like Galactolipids in Chromera velia, a Photosynthetic Relative of Malaria Parasites
por: Botté, Cyrille Y., et al.
Publicado: (2011)

Purification, Identification, and Cloning of Lysoplasmalogenase, the Enzyme That Catalyzes Hydrolysis of the Vinyl Ether Bond of Lysoplasmalogen
por: Wu, Lai-Chu, et al.
Publicado: (2011)

Antioxidant-rich spice added to hamburger meat during cooking results in reduced meat, plasma, and urine malondialdehyde concentrations(1)(2)(3)(4)
por: Li, Zhaoping, et al.
Publicado: (2010)

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
por: He, Shaoqing, et al.
Publicado: (2010)

Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid
por: Isobe, Yosuke, et al.
Publicado: (2012)

Randomized controlled study of the effect of a butter naturally enriched in trans fatty acids on blood lipids in healthy women(1)(2)(3)
por: Lacroix, Émilie, et al.
Publicado: (2012)

Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease
por: Huang, Yongcheng, et al.
Publicado: (2011)

Ceramide Kinase Regulates the Production of Tumor Necrosis Factor α (TNFα) via Inhibition of TNFα-converting Enzyme
por: Lamour, Nadia F., et al.
Publicado: (2011)

Functional and Topological Analysis of Yeast Acyl-CoA:Diacylglycerol Acyltransferase 2, an Endoplasmic Reticulum Enzyme Essential for Triacylglycerol Biosynthesis
por: Liu, Qin, et al.
Publicado: (2011)

Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP: CHIMERAS AND POINT MUTANTS IDENTIFY INTRACELLULAR AMINO-TERMINAL RESIDUES INVOLVED IN LIPID REGULATION OF P2X1 RECEPTORS
por: Allsopp, Rebecca C., et al.
Publicado: (2010)

Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis Are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1
por: Calandria, Jorgelina M., et al.
Publicado: (2012)

Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation
por: Thomas, Christopher P., et al.
Publicado: (2010)

Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response
por: Ariyama, Hiroyuki, et al.
Publicado: (2010)

Metabolic and Transcriptional Responses of Glycerolipid Pathways to a Perturbation of Glycerol 3-Phosphate Metabolism in Arabidopsis
por: Shen, Wenyun, et al.
Publicado: (2010)

Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages
por: Aflaki, Elma, et al.
Publicado: (2011)

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase
por: Chandak, Prakash G., et al.
Publicado: (2010)

Kdo(2)-Lipid A, a TLR4-specific Agonist, Induces de Novo Sphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy
por: Sims, Kacee, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_r2apsvuqr837nu4245og3638ba