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From reads to regions: a Bioconductor workflow to detect differential binding in ChIP-seq data

Chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) is widely used to identify the genomic binding sites for protein of interest. Most conventional approaches to ChIP-seq data analysis involve the detection of the absolute presence (or absence) of a binding site. However, an...

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Detalles Bibliográficos
Autores principales: Lun, Aaron T. L., Smyth, Gordon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706055/
https://www.ncbi.nlm.nih.gov/pubmed/26834993
http://dx.doi.org/10.12688/f1000research.7016.2