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From reads to regions: a Bioconductor workflow to detect differential binding in ChIP-seq data
Chromatin immunoprecipitation with massively parallel sequencing (ChIP-seq) is widely used to identify the genomic binding sites for protein of interest. Most conventional approaches to ChIP-seq data analysis involve the detection of the absolute presence (or absence) of a binding site. However, an...
Autores principales: | Lun, Aaron T. L., Smyth, Gordon K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706055/ https://www.ncbi.nlm.nih.gov/pubmed/26834993 http://dx.doi.org/10.12688/f1000research.7016.2 |
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