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Exendin-4 promotes extracellular-superoxide dismutase expression in A549 cells through DNA demethylation

Exendin-4 is an agonist of the glucagon-like peptide 1 receptor (GLP-1R) and is used in the treatment of type 2 diabetes. Since human GLP-1R has been identified in various cells besides pancreatic cells, exendin-4 is expected to exert extrapancreatic actions. It has also been suggested to affect gen...

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Detalles Bibliográficos
Autores principales: Yasuda, Hiroyuki, Mizukami, Koji, Hayashi, Mutsuna, Kamiya, Tetsuro, Hara, Hirokazu, Adachi, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706090/
https://www.ncbi.nlm.nih.gov/pubmed/26798195
http://dx.doi.org/10.3164/jcbn.15-16