NEDD4-mediated HSF1 degradation underlies α-synucleinopathy

Cellular protein homeostasis is achieved by a delicate network of molecular chaperones and various proteolytic processes such as ubiquitin–proteasome system (UPS) to avoid a build-up of misfolded protein aggregates. The latter is a common denominator of neurodegeneration. Neurons are found to be par...

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Detalles Bibliográficos
Autores principales: Kim, Eunhee, Wang, Bin, Sastry, Namratha, Masliah, Eliezer, Nelson, Peter T., Cai, Huaibin, Liao, Francesca-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706110/
https://www.ncbi.nlm.nih.gov/pubmed/26503960
http://dx.doi.org/10.1093/hmg/ddv445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706110/
https://www.ncbi.nlm.nih.gov/pubmed/26503960
http://dx.doi.org/10.1093/hmg/ddv445

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