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Dasatinib as a treatment for Duchenne muscular dystrophy

Identification of a systemically acting and universal small molecule therapy for Duchenne muscular dystrophy would be an enormous advance for this condition. Based on evidence gained from studies on mouse genetic models, we have identified tyrosine phosphorylation and degradation of β-dystroglycan a...

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Detalles Bibliográficos
Autores principales: Lipscomb, Leanne, Piggott, Robert W., Emmerson, Tracy, Winder, Steve J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706114/
https://www.ncbi.nlm.nih.gov/pubmed/26604135
http://dx.doi.org/10.1093/hmg/ddv469