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MiR-124 Promote Neurogenic Transdifferentiation of Adipose Derived Mesenchymal Stromal Cells Partly through RhoA/ROCK1, but Not ROCK2 Signaling Pathway

OBJECTIVE: Some recent studies suggest that multiple miRNAs might regulate neurogenic transdifferentiation of mesenchymal stromal cells (MSCs). In the present study, we hypothesized that the miR-124 can repress the expression of RhoA upon the neurogenesis of adipose derived MSCs (ADMSCs). METHODS: M...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Wang, Desheng, Guo, Dawen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706435/
https://www.ncbi.nlm.nih.gov/pubmed/26745800
http://dx.doi.org/10.1371/journal.pone.0146646