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The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex

The Rvb1/Rvb2 complex is an essential component of many cellular pathways. The Rvb1/Rvb2 complex forms a dodecameric assembly where six copies of each subunit form two heterohexameric rings. However, due to conformational variability, the way the two rings pack together is still not fully understood...

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Detalles Bibliográficos
Autores principales: Silva-Martin, Noella, Daudén, María I., Glatt, Sebastian, Hoffmann, Niklas A., Kastritis, Panagiotis, Bork, Peer, Beck, Martin, Müller, Christoph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706439/
https://www.ncbi.nlm.nih.gov/pubmed/26745716
http://dx.doi.org/10.1371/journal.pone.0146457