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Synergistic suppression of the PI3K inhibitor CAL-101 with bortezomib on mantle cell lymphoma growth

OBJECTIVE: To investigate the effects of CAL-101, particularly when combined with bortezomib (BTZ) on mantle cell lymphoma (MCL) cells, and to explore its relative mechanisms. METHODS: MTT assay was applied to detect the inhibitory effects of different concentrations of CAL-101. MCL cells were divid...

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Detalles Bibliográficos
Autores principales: Qu, Fu-Lian, Xia, Bing, Li, Su-Xia, Tian, Chen, Yang, Hong-Liang, Li, Qian, Wang, Ya-Fei, Yu, Yong, Zhang, Yi-Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706520/
https://www.ncbi.nlm.nih.gov/pubmed/26779377
http://dx.doi.org/10.7497/j.issn.2095-3941.2015.0013