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ASIC subunit ratio and differential surface trafficking in the brain

BACKGROUND: Acid-sensing ion channels (ASICs) are key mediators of acidosis-induced responses in neurons. However, little is known about the relative abundance of different ASIC subunits in the brain. Such data are fundamental for interpreting the relative contribution of ASIC1a homomers and 1a/2 he...

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Detalles Bibliográficos
Autores principales: Wu, Junjun, Xu, Yuanyuan, Jiang, Yu-Qing, Xu, Jiangping, Hu, Youjia, Zha, Xiang-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706662/
https://www.ncbi.nlm.nih.gov/pubmed/26746198
http://dx.doi.org/10.1186/s13041-016-0185-7