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Clinical features and outcomes of germline mutation BRCA1-linked versus sporadic ovarian cancer patients

BACKGROUND: The role of germline mutations in BRCA1 and BRCA2 genes in the risk of the development of ovarian cancer is clinically well established. BRCA1/2 testing seems to have increasing role in clinical management in patients with advanced ovarian cancer who require treatment with poly(ADP-ribos...

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Detalles Bibliográficos
Autores principales: Synowiec, Agnieszka, Wcisło, Gabriel, Bodnar, Lubomir, Górski, Bohdan, Szenajch, Jolanta, Szarlej-Wcisło, Katarzyna, Szczylik, Cezary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706695/
https://www.ncbi.nlm.nih.gov/pubmed/26753012
http://dx.doi.org/10.1186/s13053-015-0044-z