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Clinical features and outcomes of germline mutation BRCA1-linked versus sporadic ovarian cancer patients
BACKGROUND: The role of germline mutations in BRCA1 and BRCA2 genes in the risk of the development of ovarian cancer is clinically well established. BRCA1/2 testing seems to have increasing role in clinical management in patients with advanced ovarian cancer who require treatment with poly(ADP-ribos...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706695/ https://www.ncbi.nlm.nih.gov/pubmed/26753012 http://dx.doi.org/10.1186/s13053-015-0044-z |