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Post-CNS-inflammation expression of CXCL12 promotes the endogenous myelin/neuronal repair capacity following spontaneous recovery from multiple sclerosis-like disease

BACKGROUND: Demyelination and axonal degeneration, hallmarks of multiple sclerosis (MS), are associated with the central nervous system (CNS) inflammation facilitated by C-X-C motif chemokine 12 (CXCL12) chemokine. Both in MS and in experimental autoimmune encephalomyelitis (EAE), the deleterious CN...

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Detalles Bibliográficos
Autores principales: Zilkha-Falb, Rina, Kaushansky, Nathali, Kawakami, Naoto, Ben-Nun, Avraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706716/
https://www.ncbi.nlm.nih.gov/pubmed/26747276
http://dx.doi.org/10.1186/s12974-015-0468-4