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Ablating hedgehog signaling in tenocytes during development impairs biomechanics and matrix organization of the adult murine patellar tendon enthesis

Restoring the native structure of the tendon enthesis, where collagen fibers of the midsubstance are integrated within a fibrocartilaginous structure, is problematic following injury. As current surgical methods fail to restore this region adequately, engineers, biologists, and clinicians are workin...

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Detalles Bibliográficos
Autores principales: Breidenbach, Andrew P., Aschbacher‐Smith, Lindsey, Lu, Yinhui, Dyment, Nathaniel A., Liu, Chia‐Feng, Liu, Han, Wylie, Chris, Rao, Marepalli, Shearn, Jason T., Rowe, David W., Kadler, Karl E., Jiang, Rulang, Butler, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706742/
https://www.ncbi.nlm.nih.gov/pubmed/25807894
http://dx.doi.org/10.1002/jor.22899