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APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complex

Phosphoinositides are signalling lipids that are crucial for major signalling events as well as established regulators of membrane trafficking. Control of endosomal sorting and endosomal homeostasis requires phosphatidylinositol-3-phosphate (PI(3)P) and phosphatidylinositol-3,5-bisphosphate (PI(3,5)...

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Detalles Bibliográficos
Autores principales: Currinn, Heather, Guscott, Benjamin, Balklava, Zita, Rothnie, Alice, Wassmer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706845/
https://www.ncbi.nlm.nih.gov/pubmed/26216398
http://dx.doi.org/10.1007/s00018-015-1993-0